NB-110 is a novel ophthalmic formulation comprising a synthetic cannabinoid Nabilone in the absence of any preservative. The formulation mimicking human tear enables efficacious delivery through cornea to retina and optical nerves in the back of eye.
Nabilone is a CB1/CB2 receptor agonist. Nabilone is crystalline and stable under heat, light and oxygen, an advantage over other cannabinoids (dronabinol, cannabidiol).
NB-110 lowers interocular pressure of glaucoma patients and could protect optical nerves.
The combination makes this drug unique and differentiates from marketed glaucoma medications.